Publications – Center for Epigenetics & Metabolism

The following are scientific articles published by members of the CEM:

2023

Allayee, H., Farber, C. R., Seldin, M. M., Williams, E. G., James, D. E., & Lusis, A. J. (2023). Systems genetics approaches for understanding complex traits with relevance for human disease. eLife, 12, e91004. https://doi.org/10.7554/eLife.91004
Almet, A. A., Yuan, H., Annusver, K., Ramos, R., Liu, Y., Wiedemann, J., Sorkin, D. H., Landén, N. X., Sonkoly, E., Haniffa, M., Nie, Q., Lichtenberger, B. M., Luecken, M. D., Andersen, B., Tsoi, L. C., Watt, F. M., Gudjonsson, J. E., Plikus, M. V., & Kasper, M. (2023). A Roadmap for a Consensus Human Skin Cell Atlas and Single-Cell Data Standardization. The Journal of investigative dermatology, 143(9), 1667–1677. https://doi.org/10.1016/j.jid.2023.03.1679
Aran, Ö., Swales, D. A., Bailey, N. A., Korja, R., Holmberg, E., Eskola, E., Nolvi, S., Perasto, L., Nordenswan, E., Karlsson, H., Karlsson, L., Sandman, C. A., Stern, H. S., Baram, T. Z., Glynn, L. M., & Davis, E. P. (2023). Across ages and places: Unpredictability of maternal sensory signals and child internalizing behaviors. Journal of affective disorders, 347, 557–567. Advance online publication. https://doi.org/10.1016/j.jad.2023.11.068
Baldi, P. F., Abdelkarim, S., Liu, J., To, J. K., Ibarra, M. D., & Browne, A. W. (2023). Vitreoretinal Surgical Instrument Tracking in Three Dimensions Using Deep Learning. Translational vision science & technology, 12(1), 20. https://doi.org/10.1167/tvst.12.1.20
Bastard, P., Vazquez, S. E., Liu, J., Laurie, M. T., Wang, C. Y., Gervais, A., Le Voyer, T., Bizien, L., Zamecnik, C., Philippot, Q., Rosain, J., Catherinot, E., Willmore, A., Mitchell, A. M., Bair, R., Garçon, P., Kenney, H., Fekkar, A., Salagianni, M., Poulakou, G., … DeRisi, J. L. (2023). Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs. Science immunology, 8(90), eabp8966. https://doi.org/10.1126/sciimmunol.abp8966
Berezin, C. T., Aguilera, L. U., Billerbeck, S., Bourne, P. E., Densmore, D., Freemont, P., Gorochowski, T. E., Hernandez, S. I., Hillson, N. J., King, C. R., Köpke, M., Ma, S., Miller, K. M., Moon, T. S., Moore, J. H., Munsky, B., Myers, C. J., Nicholas, D. A., Peccoud, S. J., Zhou, W., … Peccoud, J. (2023). Ten simple rules for managing laboratory information. PLoS computational biology, 19(12), e1011652. https://doi.org/10.1371/journal.pcbi.1011652
Birnie, M. T., Short, A. K., de Carvalho, G. B., Taniguchi, L., Gunn, B. G., Pham, A. L., Itoga, C. A., Xu, X., Chen, L. Y., Mahler, S. V., Chen, Y., & Baram, T. Z. (2023). Stress-induced plasticity of a CRH/GABA projection disrupts reward behaviors in mice. Nature communications, 14(1), 1088. https://doi.org/10.1038/s41467-023-36780-x
Blair, M. C., Neinast, M. D., Jang, C., Chu, Q., Jung, J. W., Axsom, J., Bornstein, M. R., Thorsheim, C., Li, K., Hoshino, A., Yang, S., Roth Flach, R. J., Zhang, B. B., Rabinowitz, J. D., & Arany, Z. (2023). Branched-chain amino acid catabolism in muscle affects systemic BCAA levels but not insulin resistance. Nature metabolism, 5(4), 589–606. https://doi.org/10.1038/s42255-023-00794-y
Blumberg, B., Cheng-An Chang, R., Egusquiza, R., Amato, A., Li, Z., Joloya, E., Wheeler, H., Nguyen, A., Shioda, K., Odajima, J., Lawrence, M., & Shioda, T. (2023). Heritable changes in chromatin contacts linked to transgenerational obesity. Research square, rs.3.rs-3570919. https://doi.org/10.21203/rs.3.rs-3570919/v1
Bocci, F., Jia, D., Nie, Q., Jolly, M. K., & Onuchic, J. (2023). Theoretical and computational tools to model multistable gene regulatory networks. Reports on progress in physics. Physical Society (Great Britain), 86(10), 10.1088/1361-6633/acec88. https://doi.org/10.1088/1361-6633/acec88
Cang, Z., Zhao, Y., Almet, A. A., Stabell, A., Ramos, R., Plikus, M. V., Atwood, S. X., & Nie, Q. (2023). Screening cell-cell communication in spatial transcriptomics via collective optimal transport. Nature methods, 20(2), 218–228. https://doi.org/10.1038/s41592-022-01728-4
Cao, X., Xu, J., Lin, Y. L., Cabrera, R. M., Chen, Q., Zhang, C., Steele, J. W., Han, X., Gross, S. S., Wlodarczyk, B. J., Lupski, J. R., Li, W., Wang, H., Finnell, R. H., & Lei, Y. (2023). Excess folic acid intake increases DNA de novo point mutations. Cell discovery, 9(1), 22. https://doi.org/10.1038/s41421-022-00512-0
Chang, R. C., Joloya, E. M., Li, Z., Shoucri, B. M., Shioda, T., & Blumberg, B. (2023). miR-223 Plays a Key Role in Obesogen-Enhanced Adipogenesis in Mesenchymal Stem Cells and in Transgenerational Obesity. Endocrinology, 164(5), bqad027. https://doi.org/10.1210/endocr/bqad027
Chella Krishnan, K., El Hachem, E. J., Keller, M. P., Patel, S. G., Carroll, L., Vegas, A. D., Gerdes Gyuricza, I., Light, C., Cao, Y., Pan, C., Kaczor-Urbanowicz, K. E., Shravah, V., Anum, D., Pellegrini, M., Lee, C. F., Seldin, M. M., Rosenthal, N. A., Churchill, G. A., Attie, A. D., Parker, B., … Lusis, A. J. (2023). Genetic architecture of heart mitochondrial proteome influencing cardiac hypertrophy. eLife, 12, e82619. https://doi.org/10.7554/eLife.82619
Chen, F., Sarver, D. C., Saqib, M., Velez, L. M., Aja, S., Seldin, M. M., & Wong, G. W. (2023). Loss of CTRP10 results in female obesity with preserved metabolic health. bioRxiv : the preprint server for biology, 2023.11.01.565163. https://doi.org/10.1101/2023.11.01.565163
Chen, F., Sarver, D. C., Saqib, M., Zhou, M., Aja, S., Seldin, M. M., & Wong, G. W. (2023). CTRP13 ablation improves systemic glucose and lipid metabolism. Molecular metabolism, 78, 101824. https://doi.org/10.1016/j.molmet.2023.101824
Cho, S., Chun, Y., He, L., Ramirez, C. B., Ganesh, K. S., Jeong, K., Song, J., Cheong, J. G., Li, Z., Choi, J., Kim, J., Koundouros, N., Ding, F., Dephoure, N., Jang, C., Blenis, J., & Lee, G. (2023). FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1. Molecular cell, 83(16), 3010–3026.e8. https://doi.org/10.1016/j.molcel.2023.07.017
Clifford, B. L., Jarrett, K. E., Cheng, J., Cheng, A., Seldin, M., Morand, P., Lee, R., Chen, M., Baldan, A., de Aguiar Vallim, T. Q., & Tarling, E. J. (2023). RNF130 Regulates LDLR Availability and Plasma LDL Cholesterol Levels. Circulation research, 132(7), 849–863. https://doi.org/10.1161/CIRCRESAHA.122.321938
Cornuti, S., Chen, S., Lupori, L., Finamore, F., Carli, F., Samad, M., Fenizia, S., Caldarelli, M., Damiani, F., Raimondi, F., Mazziotti, R., Magnan, C., Rocchiccioli, S., Gastaldelli, A., Baldi, P., & Tognini, P. (2023). Brain histone beta-hydroxybutyrylation couples metabolism with gene expression. Cellular and molecular life sciences : CMLS, 80(1), 28. https://doi.org/10.1007/s00018-022-04673-9
Coulis, G., Jaime, D., Guerrero-Juarez, C., Kastenschmidt, J. M., Farahat, P. K., Nguyen, Q., Pervolarakis, N., McLinden, K., Thurlow, L., Movahedi, S., Hughes, B. S., Duarte, J., Sorn, A., Montoya, E., Mozaffar, I., Dragan, M., Othy, S., Joshi, T., Hans, C. P., Kimonis, V., … Villalta, S. A. (2023). Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis. Science advances, 9(27), eadd9984. https://doi.org/10.1126/sciadv.add9984
Coulis, G., Jaime, D., Guerrero-Juarez, C., Kastenschmidt, J. M., Farahat, P. K., Nguyen, Q., Pervolarakis, N., McLinden, K., Thurlow, L., Movahedi, S., Duarte, J., Sorn, A., Montoya, E., Mozaffar, I., Dragan, M., Othy, S., Joshi, T., Hans, C. P., Kimonis, V., MacLean, A. L., … Villalta, S. A. (2023). Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis. bioRxiv : the preprint server for biology, 2023.04.18.537253. https://doi.org/10.1101/2023.04.18.537253
Cui, Y., Arnold, F. J., Peng, F., Wang, D., Li, J. S., Michels, S., Wagner, E. J., La Spada, A. R., & Li, W. (2023). Alternative polyadenylation transcriptome-wide association study identifies APA-linked susceptibility genes in brain disorders. Nature communications, 14(1), 583. https://doi.org/10.1038/s41467-023-36311-8
Cunha, Y. G. O., do Amaral, G. C. B., Felix, A. A., Blumberg, B., & Amato, A. A. (2023). Early-life exposure to endocrine-disrupting chemicals and autistic traits in childhood and adolescence: a systematic review of epidemiological studies. Frontiers in endocrinology, 14, 1184546. https://doi.org/10.3389/fendo.2023.1184546
DeRogatis, J. M., Neubert, E. N., Viramontes, K. M., Henriquez, M. L., Nicholas, D. A., & Tinoco, R. (2023). Cell-Intrinsic CD38 Expression Sustains Exhausted CD8⁺ T Cells by Regulating Their Survival and Metabolism during Chronic Viral Infection. Journal of virology, 97(4), e0022523. https://doi.org/10.1128/jvi.00225-23
Doshi, M. B., Lee, N., Tseyang, T., Ponomarova, O., Goel, H. L., Spears, M., Li, R., Zhu, L. J., Ashwood, C., Simin, K., Jang, C., Mercurio, A. M., Walhout, A. J. M., Spinelli, J. B., & Kim, D. (2023). Disruption of sugar nucleotide clearance is a therapeutic vulnerability of cancer cells. Nature, 623(7987), 625–632. https://doi.org/10.1038/s41586-023-06676-3
Dragan, M., Chen, Z., Li, Y., Le, J., Sun, P., Haensel, D., Sureshchandra, S., Pham, A., Lu, E., Pham, K. T., Verlande, A., Vu, R., Gutierrez, G., Li, W., Jang, C., Masri, S., & Dai, X. (2023). Ovol1/2 loss-induced epidermal defects elicit skin immune activation and alter global metabolism. EMBO reports, 24(7), e56214. https://doi.org/10.15252/embr.202256214
Du, L., Yang, H., Ren, Y., Ding, Y., Xu, Y., Zi, X., Liu, H., & He, P. (2023). Inhibition of LSD1 induces ferroptosis through the ATF4-xCT pathway and shows enhanced anti-tumor effects with ferroptosis inducers in NSCLC. Cell death & disease, 14(11), 716. https://doi.org/10.1038/s41419-023-06238-5
Fallatah, M. M. J., Law, F. V., Chow, W. A., & Kaiser, P. (2023). Small-molecule correctors and stabilizers to target p53. Trends in pharmacological sciences, 44(5), 274–289. https://doi.org/10.1016/j.tips.2023.02.007
Ghirardini, E., Sagona, G., Marquez-Galera, A., Calugi, F., Navarron, C. M., Cacciante, F., Chen, S., Di Vetta, F., Dadà, L., Mazziotti, R., Lupori, L., Putignano, E., Baldi, P., Lopez-Atalaya, J. P., Pizzorusso, T., & Baroncelli, L. (2023). Cell-specific vulnerability to metabolic failure: the crucial role of parvalbumin expressing neurons in creatine transporter deficiency. Acta neuropathologica communications, 11(1), 34. https://doi.org/10.1186/s40478-023-01533-w
Goyal, J., Ng, D. Q., Zhang, K., Chan, A., Lee, J., Zheng, K., Hurley-Kim, K., Nguyen, L., He, L., Nguyen, M., McBane, S., Li, W., & Cadiz, C. L. (2023). Using machine learning to develop a clinical prediction model for SSRI-associated bleeding: a feasibility study. BMC medical informatics and decision making, 23(1), 105. https://doi.org/10.1186/s12911-023-02206-3
Green, C. L., Trautman, M. E., Chaiyakul, K., Jain, R., Alam, Y. H., Babygirija, R., Pak, H. H., Sonsalla, M. M., Calubag, M. F., Yeh, C. Y., Bleicher, A., Novak, G., Liu, T. T., Newman, S., Ricke, W. A., Matkowskyj, K. A., Ong, I. M., Jang, C., Simcox, J., & Lamming, D. W. (2023). Dietary restriction of isoleucine increases healthspan and lifespan of genetically heterogeneous mice. Cell metabolism, 35(11), 1976–1995.e6. https://doi.org/10.1016/j.cmet.2023.10.005
Guan, D., Bae, H., Zhou, D., Chen, Y., Jiang, C., La, C. M., Xiao, Y., Zhu, K., Hu, W., Trinh, T. M., Liu, P., Xiong, Y., Cai, B., Jang, C., & Lazar, M. A. (2023). Hepatocyte SREBP signaling mediates clock communication within the liver. The Journal of clinical investigation, 133(8), e163018. https://doi.org/10.1172/JCI163018
Guo, Y. J., Pang, J. R., Zhang, Y., Li, Z. R., Zi, X. L., Liu, H. M., Wang, N., Zhao, L. J., Gao, Y., Wang, B., Herdewijn, P., Jin, C. Y., Liu, Y., & Zheng, Y. C. (2024). Neddylation-dependent LSD1 destabilization inhibits the stemness and chemoresistance of gastric cancer. International journal of biological macromolecules, 254(Pt 3), 126801. https://doi.org/10.1016/j.ijbiomac.2023.126801
Haley, J. A., Jang, C., & Guertin, D. A. (2023). A new era of understanding in vivo metabolic flux in thermogenic adipocytes. Current opinion in genetics & development, 83, 102112. https://doi.org/10.1016/j.gde.2023.102112
He, C., Zhou, P., & Nie, Q. (2023). exFINDER: identify external communication signals using single-cell transcriptomics data. bioRxiv : the preprint server for biology, 2023.03.24.533888. https://doi.org/10.1101/2023.03.24.533888
He, C., Zhou, P., & Nie, Q. (2023). exFINDER: identify external communication signals using single-cell transcriptomics data. Nucleic acids research, 51(10), e58. https://doi.org/10.1093/nar/gkad262
Heindel, J. J., Alvarez, J. A., Atlas, E., Cave, M. C., Chatzi, V. L., Collier, D., Corkey, B., Fischer, D., Goran, M. I., Howard, S., Kahan, S., Kayhoe, M., Koliwad, S., Kotz, C. M., La Merrill, M., Lobstein, T., Lumeng, C., Ludwig, D. S., Lustig, R. H., Myers, P., … Blumberg, B. (2023). Obesogens and Obesity: State-of-the-Science and Future Directions Summary from a Healthy Environment and Endocrine Disruptors Strategies Workshop. The American journal of clinical nutrition, 118(1), 329–337. https://doi.org/10.1016/j.ajcnut.2023.05.024
Hernandez, S. J., Lim, R. G., Onur, T., Dane, M. A., Smith, R., Wang, K., Jean, G. E., Reyes-Ortiz, A., Devlin, K., Miramontes, R., Wu, J., Casale, M., Kilburn, D., Heiser, L. M., Korkola, J. E., Van Vactor, D., Botas, J., Thompson-Peer, K. L., & Thompson, L. M. (2023). An altered extracellular matrix-integrin interface contributes to Huntington’s disease-associated CNS dysfunction in glial and vascular cells. Human molecular genetics, 32(9), 1483–1496. https://doi.org/10.1093/hmg/ddac303
Holley, S. M., Reidling, J. C., Cepeda, C., Wu, J., Lim, R. G., Lau, A., Moore, C., Miramontes, R., Fury, B., Orellana, I., Neel, M., Coleal-Bergum, D., Monuki, E. S., Bauer, G., Meshul, C. K., Levine, M. S., & Thompson, L. M. (2023). Transplanted human neural stem cells rescue phenotypes in zQ175 Huntington’s disease mice and innervate the striatum. Molecular therapy : the journal of the American Society of Gene Therapy, 31(12), 3545–3563. https://doi.org/10.1016/j.ymthe.2023.10.003
Isozaki, H., Sakhtemani, R., Abbasi, A., Nikpour, N., Stanzione, M., Oh, S., Langenbucher, A., Monroe, S., Su, W., Cabanos, H. F., Siddiqui, F. M., Phan, N., Jalili, P., Timonina, D., Bilton, S., Gomez-Caraballo, M., Archibald, H. L., Nangia, V., Dionne, K., Riley, A., … Hata, A. N. (2023). Therapy-induced APOBEC3A drives evolution of persistent cancer cells. Nature, 620(7973), 393–401. https://doi.org/10.1038/s41586-023-06303-1
Jirsaraie, R. J., Palma, A. M., Small, S. L., Sandman, C. A., Davis, E. P., Baram, T. Z., Stern, H., Glynn, L. M., & Yassa, M. A. (2023). Prenatal Exposure to Maternal Mood Entropy Is Associated With a Weakened and Inflexible Salience Network in Adolescence. Biological psychiatry. Cognitive neuroscience and neuroimaging, S2451-9022(23)00215-X. Advance online publication. https://doi.org/10.1016/j.bpsc.2023.08.002
Johnson, M. R., Li, S., Guerrero-Juarez, C. F., Miller, P., Brack, B. J., Mereby, S. A., Moreno, J. A., Feigin, C. Y., Gaska, J., Rivera-Perez, J. A., Nie, Q., Ploss, A., Shvartsman, S. Y., & Mallarino, R. (2023). A multifunctional Wnt regulator underlies the evolution of rodent stripe patterns. Nature ecology & evolution, 7(12), 2143–2159. https://doi.org/10.1038/s41559-023-02213-7
Jonnakuti, V. S., Ji, P., Gao, Y., Lin, A., Chu, Y., Elrod, N., Huang, K. L., Li, W., Yalamanchili, H. K., & Wagner, E. J. (2023). NUDT21 alters glioma migration through differential alternative polyadenylation of LAMC1. Journal of neuro-oncology, 163(3), 623–634. https://doi.org/10.1007/s11060-023-04370-y
Jurrjens, A. W., Seldin, M. M., Giles, C., Meikle, P. J., Drew, B. G., & Calkin, A. C. (2023). The potential of integrating human and mouse discovery platforms to advance our understanding of cardiometabolic diseases. eLife, 12, e86139. https://doi.org/10.7554/eLife.86139
Kaakour, D., Fortin, B., Masri, S., & Rezazadeh, A. (2023). Circadian Clock Dysregulation and Prostate Cancer: A Molecular and Clinical Overview. Clinical Medicine Insights. Oncology, 17, 11795549231211521. https://doi.org/10.1177/11795549231211521
Kaiser, P. K., Karpecki, P. M., Regillo, C. D., Baumal, C., Ryan, E. H., Ip, M. S., Modi, Y., Yeu, E., Nijm, L., Farid, M., Rebenitsch, R. L., Kim, T., Shechtman, D. L., Nichols, K., Schweitzer, J., Dunbar, M. T., Rafieetary, M. R., & Donnenfeld, E. D. (2023). Geographic Atrophy Management Consensus (GA-MAC): a Delphi panel study on identification, diagnosis and treatment. BMJ open ophthalmology, 8(1), e001395. https://doi.org/10.1136/bmjophth-2023-001395
Kim, J., Chun, Y., Ramirez, C. B., Hoffner, L. A., Jung, S., Jang, K. H., Rubtsova, V. I., Jang, C., & Lee, G. (2023). MAPK13 stabilization via m⁶A mRNA modification limits anticancer efficacy of rapamycin. The Journal of biological chemistry, 299(9), 105175. https://doi.org/10.1016/j.jbc.2023.105175
Kim, J., Chun, Y., Ramirez, C. B., Hoffner, L. A., Jung, S., Jang, K. H., Rubtsova, V. I., Jang, C., & Lee, G. (2023). MAPK13 stabilization via m⁶A mRNA modification limits anticancer efficacy of rapamycin. The Journal of biological chemistry, 299(9), 105175. https://doi.org/10.1016/j.jbc.2023.105175
Kishore, C., & Zi, X. (2023). Wnt Signaling and Therapeutic Resistance in Castration-Resistant Prostate Cancer. Current pharmacology reports, 9(5), 261–274. https://doi.org/10.1007/s40495-023-00333-z
Kloc, M. L., Chen, Y., Daglian, J. M., Holmes, G. L., Baram, T. Z., & Barry, J. M. (2023). Spatial learning impairments and discoordination of entorhinal-hippocampal circuit coding following prolonged febrile seizures. Hippocampus, 33(8), 970–992. https://doi.org/10.1002/hipo.23541
Kooiker, C. L., Chen, Y., Birnie, M. T., & Baram, T. Z. (2023). Genetic Tagging Uncovers a Robust, Selective Activation of the Thalamic Paraventricular Nucleus by Adverse Experiences Early in Life. Biological psychiatry global open science, 3(4), 746–755. https://doi.org/10.1016/j.bpsgos.2023.01.002
Lee, B. J., Griffin, S. P., Doh, J., Chan, A., Ciurea, S. O., Jeyakumar, D., Fleischman, A. G., Naqvi, K., Pannunzio, N. R., O’Brien, S., & Kongtim, P. (2023). HyperCVAD versus pegaspargase-containing regimens for Hispanic adults with newly diagnosed B-cell acute lymphoblastic leukemia. European journal of haematology, 10.1111/ejh.14125. Advance online publication. https://doi.org/10.1111/ejh.14125
Lee, H., Blumberg, B., Lawrence, M. S., & Shioda, T. (2023). Revisiting the use of structural similarity index in Hi-C. Nature genetics, 55(12), 2049–2052. https://doi.org/10.1038/s41588-023-01594-6
Lee, J., Chen, S., Monfared, R. V., Derdeyn, P., Leong, K., Chang, T., Beier, K., Baldi, P., & Alachkar, A. (2023). Reanalysis of primate brain circadian transcriptomics reveals connectivity-related oscillations. iScience, 26(10), 107810. https://doi.org/10.1016/j.isci.2023.107810
Lee, G., Wong, C., Cho, A., West, J. J., Crawford, A. J., Russo, G. C., Si, B. R., Kim, J., Hoffner, L., Jang, C., Jung, M., Leone, R. D., Konstantopoulos, K., Ewald, A. J., Wirtz, D., & Jeong, S. (2023). Serine synthesis pathway upregulated by E-cadherin is essential for the proliferation and metastasis of breast cancers. bioRxiv : the preprint server for biology, 2023.05.24.541452. https://doi.org/10.1101/2023.05.24.541452
Lei, Y., Yin, Z., Lu, X., Zhang, Q., Gong, J., Cai, B., Cai, C., Chai, Q., Chen, H., Chen, R., Chen, S., Chen, W., Cheng, J., Chi, X., Dai, H., Feng, X., Geng, G., Hu, J., Hu, S., Huang, C., … He, K. (2023). The 2022 report of synergetic roadmap on carbon neutrality and clean air for China: Accelerating transition in key sectors. Environmental science and ecotechnology, 19, 100335. https://doi.org/10.1016/j.ese.2023.100335
Li, L., Ma, X., Cui, Y., Rotival, M., Chen, W., Zou, X., Ding, R., Qin, Y., Wang, Q., Quintana-Murci, L., & Li, W. (2023). Immune-response 3’UTR alternative polyadenylation quantitative trait loci contribute to variation in human complex traits and diseases. Nature communications, 14(1), 8347. https://doi.org/10.1038/s41467-023-44191-1
Liau, E. S., Jin, S., Chen, Y. C., Liu, W. S., Calon, M., Nedelec, S., Nie, Q., & Chen, J. A. (2023). Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons. Nature communications, 14(1), 46. https://doi.org/10.1038/s41467-022-35574-x
Lin, L., Jung, K. M., Lee, H. L., Le, J., Colleluori, G., Wood, C., Palese, F., Squire, E., Ramirez, J., Su, S., Torrens, A., Fotio, Y., Tang, L., Yu, C., Yang, Q., Huang, L., DiPatrizio, N., Jang, C., Cinti, S., & Piomelli, D. (2023). Adolescent exposure to low-dose THC disrupts energy balance and adipose organ homeostasis in adulthood. Cell metabolism, 35(7), 1227–1241.e7. https://doi.org/10.1016/j.cmet.2023.05.002
Liu, L., Yu, A. M., Wang, X., Soles, L. V., Teng, X., Chen, Y., Yoon, Y., Sarkan, K. S. K., Valdez, M. C., Linder, J., England, W., Spitale, R., Yu, Z., Marazzi, I., Qiao, F., Li, W., Seelig, G., & Shi, Y. (2023). The anticancer compound JTE-607 reveals hidden sequence specificity of the mRNA 3′ processing machinery. Nature structural & molecular biology, 30(12), 1947–1957. https://doi.org/10.1038/s41594-023-01161-x
Liu, Z., Song, L., Xie, J., Wu, X. R., Gin, G. E., Wang, B., Uchio, E., & Zi, X. (2023). Kavalactone Kawain Impedes Urothelial Tumorigenesis in UPII-Mutant Ha-Ras Mice via Inhibition of mTOR Signaling and Alteration of Cancer Metabolism. Molecules (Basel, Switzerland), 28(4), 1666. https://doi.org/10.3390/molecules28041666
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2013-2020

Alshetaiwi H, Pervolarakis N, McIntyre LL, Ma D, Nguyen QH, Rath JA, Nee K, Hernandez G, Evans K, Torosian L, Silva A, Walsh C, Kessenbrock K. Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomics. Science Immunology. 2020 Feb 21;5(44). pii: eaay6017. doi: 10.1126/sciimmunol.aay6017
Jalili, P., Bowen, D., Langenbucher, A., Park, S., Aguirre, K., Corcoran, R. B., Fleischman, A. G., Lawrence, M. S., Zou, L., & Buisson, R. (2020). Quantification of ongoing APOBEC3A activity in tumor cells by monitoring RNA editing at hotspots. Nature communications, 11(1), 2971. https://doi.org/10.1038/s41467-020-16802-8
Lewis, R. G., Serra, M., Radl, D., Gori, M., Tran, C., Michalak, S. E., Vanderwal, C. D., & Borrelli, E. (2020). Dopaminergic Control of Striatal Cholinergic Interneurons Underlies Cocaine-Induced Psychostimulation. Cell reports, 31(3), 107527. https://doi.org/10.1016/j.celrep.2020.107527
Sato, S., Bunney, B. G., Vawter, M. P., Bunney, W. E., & Sassone-Corsi, P. (2020). Homer1a Undergoes Bimodal Transcriptional Regulation by CREB and the Circadian Clock. Neuroscience, 434, 161–170. https://doi.org/10.1016/j.neuroscience.2020.03.031
Cervantes, M., Forné, I., Ranjit, S., Gratton, E., Imhof, A., Sassone-Corsi, P., BMAL1 associates with NOP58 in the nucleolus and contributes to pre-rRNA processing, ISCIENCE (2020), doi: https://doi.org/10.1016/j.isci.2020.101151.
Li, Y., Dammer, E. B., Gao, Y., Lan, Q., Villamil, M. A., Duong, D. M., Zhang, C., Ping, L., Lauinger, L., Flick, K., Xu, Z., Wei, W., Xing, X., Chang, L., Jin, J., Hong, X., Zhu, Y., Wu, J., Deng, Z., He, F., … Xu, P. (2019). Proteomics Links Ubiquitin Chain Topology Change to Transcription Factor Activation. Molecular cell, 76(1), 126–137.e7. https://doi.org/10.1016/j.molcel.2019.07.001
Lin, D. W., Chung, B. P., Huang, J. W., Wang, X., Huang, L., & Kaiser, P. (2019). Microhomology-based CRISPR tagging tools for protein tracking, purification, and depletion. The Journal of biological chemistry, 294(28), 10877–10885. https://doi.org/10.1074/jbc.RA119.008422
Sato S, Solanas G, Peixoto FO, Bee L, Symeonidi A, Schmidt MS, Brenner C, Masri S, Benitah SA, Sassone-Corsi P. (2017) Circadian reprogramming in the liver identifies metabolic pathways of aging.Cell. 170:664-677.
Solanas G, Peixoto FO, Perdiguero E, Jardí M, Ruiz-Bonilla V, Datta D, Symeonidi A, Castellanos A, Welz PS, Caballero JM, Sassone-Corsi P, Muñoz-Cánoves P, Benitah SA. Aged stem cells reprogram their daily rhythmic functions to adapt to stress. Cell. 170:678-692.
Tognini P, Thaiss CA, Elinav E, Sassone-Corsi P. (2017) Circadian coordination of antimicrobial responses. Cell Host Microbe. 22:185-192. Review.
Masri S, Papagiannakopoulos T, Kinouchi K, Liu Y, Cervantes M, Baldi P, Jacks T, Sassone-Corsi P. (2016) Lung adenocarcinoma distally rewires hepatic circadian homeostasis.Cell. 165:896-909.
Gao W, Wang H, Zhang L, Cao Y, Bao JZ, Liu ZX, Wang LS, Yang Q, Lu X. (2016) Retinol-binding protein 4 induces cardiomyocyte hypertrophy by activating TLR4/MyD88 pathway. Endocrinology. 157:2282-93.
Aguilar-Arnal L, Katada S, Orozco-Solis R, Sassone-Corsi P. (2015) NAD⁺-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1. Nat Struct Mol Biol. 22:312-8.
Masri S, Rigor P, Cervantes M, Ceglia N, Sebastian C, Xiao C, Roqueta-Rivera M, Deng C, Osborne TF, Mostoslavsky R, Baldi P, Sassone-Corsi P. (2014) Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism. Cell. 158:659-72.
Brami-Cherrier K, Anzalone A, Ramos M, Forne I, Macciardi F, Imhof A, Borrelli E. (2014) Epigenetic reprogramming of cortical neurons through alteration of dopaminergic circuits. Mol Psychiatry. 19:1193-200
Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT, Pirinen E, Pulinilkunnil TC, Gong F, Wang YC, Cen Y, Sauve AA, Asara JM, Peroni OD, Monia BP, Bhanot S, Alhonen L, Puigserver P, Kahn BB. (2014) Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature. 508:258-62.
Radl D, De Mei C, Chen E, Lee H, Borrelli E. (2013) Each individual isoform of the dopamine D2 receptor protects from lactotroph hyperplasia. Mol Endocrinol. 27:953-65.
Eckel-Mahan K, Patel V, de Mateo S, Orozco-Solis R, Ceglia N, Sahar S, Dilag S, Dyar K, Baldi P, Sassone-Corsi P. (2013) Reprogramming of the circadian clock by nutritional challenge. Cell. 155:1464-78.
Aguilar-Arnal L, Hakim O, Patel VR, Baldi P, Hager GH, Sassone-Corsi P. (2013) Cycles in spatial and temporal chromosomal organization driven by the circadian clock. Nat Struct Mol Biol. 20:1206-13.