Join us for a scientific symposium featuring scholars from KAIST! Speakers will discuss their biomedical research on RNA, gene regulation, and disease.

Where: David G. Sills Conference Room / Sprague Hall 105 (1st Floor)

When: Thursday, June 5 from 1:00 PM to 4:30 PM and Friday June 6 from 8:30 AM to 12:30 PM

Space is limited. RVSP required. There is no cost to attend.

Program Book

Agenda

Day 1 – Thursday, June 5:

1:00 PM Coffee

1:30 PM Welcome

Session 1. Epigenetic mechanisms of gene regulation – Chair: Yoon Ki Kim (KAIST)

1:40 PM Daeyoup Lee, PhD – Professor, Dept of Biological Sciences, KAIST

RNAPII elongation defects caused by nuclear exosome depletion alter DNA topology and reduce cohesin occupancy

2:00 PM Ivan Marazzi, PhD – Professor, Dept of Biological Chemistry; Director, Center for Epigenetics and Metabolism, UCI

Transposable elements in gene expression

2:20 PM Grace Bower – PhD Student, Evgeny Kvon Lab, Dept of Developmental and Cell Biology, UCI

Range Extender Mediates Long-Distance Enhancer Activity

2:40 PM Break

Session 2. The functions of RNA in gene regulation – Chair: Cholsoon Jang (UCI)

3:00 PM Yoon Ki Kim, PhD – Professor, Dept of Biological Sciences, KAIST

Circular RNA-induced nonsense-mediated mRNA decay

3:20 PM Yongsheng Shi, PhD – Professor, Dept of Microbiology and Molecular Genetics, UCI

The nuclear RNA degradation code in health and diseases

3:40 PM Yoosik Kim, PhD – Professor, Dept of Chemical and Biomolecular Engineering, KAIST

Utilizing double-stranded RNAs for cancer therapy

4:00 PM Ki-Jun Yoon, PhD – Assistant Professor, Dept of Biological Sciences, KAIST

Regulation of neural epitranscriptome during neuronal differentiation and synaptogenesis

4:20 PM Closing Remarks

Day 2 – Friday, June 6:

8:30 AM Coffee and Pastries

9:00 AM Welcome

Session 3. Gene regulation and cellular stress – Chair: Yoosik Kim (KAIST)

9:10 AM Chunghun Lim, PhD – Associate Professor, Dept of Biological Sciences, KAIST

Ribosome collisions and translation stress responses in human diseases

9:30 AM Thomas Martinez, PhD – Assistant Professor, Dept of Pharmaceutical Sciences, UCI

Regulation of ribosome biogenesis by a disordered nucleolar microprotein

9:50 AM Won-Ki Cho, PhD – Assistant Professor, Dept of Biological Sciences, KAIST

The role of vimentin in resolving misfolded protein aggregates under proteolytic stress

10:10 AM Minji Byun, PhD – Assistant Professor, Dept of Microbiology and Molecular Genetics, UCI

Clonal hematopoiesis-associated DNMT3A mutations derepress Polycomb Repressive Complex target genes

10:30 AM Break

Session 4. Gene regulation and tissue homeostasis – Chair: Won-Ki Cho (KAIST)

10:50 AM Seungsoo Kim, PhD – Assistant Professor, Dept of Developmental and Cell Biology, UCI

Deciphering combinatorial transcription factor control of cell identity

11:10 AM Cholsoon Jang, PhD – Assistant Professor, Dept of Biological Chemistry, UCI

Liver cancer cells evade ferroptosis through polyunsaturated fatty acid elongation

11:30 AM Yujin Chun, PhD – Postdoctoral Fellow, Gina Lee / Cholsoon Jang Lab, Dept of Microbiology and Molecular Genetics, UCI

mTORC1-dependent translational regulation of fatty acid desaturation enzymes

11:50 AM Hanseul Yang, PhD – Assistant Professor, Dept of Biological Sciences, KAIST

A novel fracture lattice in spiny mouse skin facilitates regeneration

12:10 PM Closing Remarks